## [Bioscience and Bioengineering - 2023](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering) .llnl-bg-cfc9809e { background-image: linear-gradient(rgba(0, 0, 0, 0.3), rgba(0, 0, 0, 0.3)), url(https://ldrd-annual.llnl.gov/sites/ldrd_annual/files/styles/orig/public/2020-09/subart_bio1.jpg?itok=AAEnqmqs); }# Bioscience and Bioengineering *Project Highlights* FY2023 Click on any of the project titles below to view a brief project summary, or return to our **[Project Highlights](https://ldrd-annual.llnl.gov/ldrd-annual-2023)** page to view lists of FY23 projects in other research categories. Search Project Type - Any -Disruptive ResearchExploratory ResearchFeasibility StudyLab-WideStrategic Initiative Project Status - Any -FinalContinuing | [Project Title Sort descending ](?combine=&field_project_type_target_id=All&field_project_status_value=All&order=title&sort=desc "sort by Project Title") | [Project Code](?combine=&field_project_type_target_id=All&field_project_status_value=All&order=field_release_number&sort=asc "sort by Project Code") | [Principal Investigator](?combine=&field_project_type_target_id=All&field_project_status_value=All&order=field_byline&sort=asc "sort by Principal Investigator") | [Project Type](?combine=&field_project_type_target_id=All&field_project_status_value=All&order=field_project_type&sort=asc "sort by Project Type") | [Project Status](?combine=&field_project_type_target_id=All&field_project_status_value=All&order=field_project_status&sort=asc "sort by Project Status") | |---|---|---|---|---| | [Adverse Neurological Effects of Wildfire Smoke](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/adverse-neurological-effects-wildfire-smoke) | 23-ERD-020 | Bruce Buchholz | Exploratory Research | Continuing | | [Battling Long Coronavirus Disease 2019 in the Brain: Elucidating Mechanisms of Neural Dysfunction](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/battling-long-coronavirus-disease-2019-brain-elucidating-mechanisms-neural-dysfunction) | 22-DR-007 | Heather Enright | Disruptive Research | Continuing | | [Biological Additive Manufacturing Capabilities for Enabling Rapid Response to Emerging Pathogens](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/biological-additive-manufacturing-capabilities-enabling-rapid-response-emerging-pathogens) | 21-ERD-039 | Matthew Coleman | Exploratory Research | Final | | [Carbon-14-Labeled Microbes to Track the Fates of Microbial Metabolites: A Potential Technical Approach to Define the Gut-Brain Axis in Animal Models](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/carbon-14-labeled-microbes-track-fates-microbial-metabolites-potential-technical-approach-define-gut-brain-axis-animal-models) | 22-FS-002 | Doris Lam | Feasibility Study | Final | | [Controlling Access to the Brain: Fine-Tuning Permeability of the Blood-Brain Barrier](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/controlling-access-brain-fine-tuning-permeability-blood-brain-barrier) | 22-ERD-038 | Dina Weilhammer | Exploratory Research | Continuing | | [Cure the Incurable: Supercharged Immune Cells to Fight Disease](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/cure-incurable-supercharged-immune-cells-fight-disease) | 22-LW-061 | Aimy Sebastian | Lab-Wide | Final | | [Development of Advanced Terahertz Chiroptical Spectroscopy for Biological and Chemical Security](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/development-advanced-terahertz-chiroptical-spectroscopy-biological-and-chemical-security) | 22-ERD-056 | Wonjin Choi | Exploratory Research | Continuing | | [Eavesdropping on Cancer: Developing Blood-Based Exosome Diagnostics](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/eavesdropping-cancer-developing-blood-based-exosome-diagnostics) | 21-LW-028 | Nicholas Hum | Lab-Wide | Final | | [Engineered Human Vascular Models to Study Endothelial Dysfunction in Infectious Disease](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/engineered-human-vascular-models-study-endothelial-dysfunction-infectious-disease) | 22-LW-088 | Monica Moya | Lab-Wide | Final | | [Engineering a Biosynthetic Pathway for Glycolonitrile, a High Energy Material Precursor](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/engineering-biosynthetic-pathway-glycolonitrile-high-energy-material-precursor) | 22-ERD-051 | Mimi Yung | Exploratory Research | Continuing | | [Engineering Bacillus Subtilis for Controlled Gaseous Nitrogen Fixation to Reduce Artificial Nitrogen Utilization and Enhance Microbial Community Function](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/engineering-bacillus-subtilis-controlled-gaseous-nitrogen-fixation-reduce-artificial-nitrogen-utilization-and-enhance-microbial-community-function) | 23-LW-014 | Cody Madsen | Lab-Wide | Continuing | | [Fiery Effects of Wildfire Smoke Inhalation](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/fiery-effects-wildfire-smoke-inhalation) | 22-LW-001 | Melanie Mendez | Lab-Wide | Final | | [Fungal Pneumonia: Understanding Immune Vulnerabilities that Cause Valley Fever](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/fungal-pneumonia-understanding-immune-vulnerabilities-cause-valley-fever) | 22-ERD-010 | Dina Weilhammer | Exploratory Research | Continuing | | [Graph-Based Modeling for Detection and Tracking of Sarin-Surrogate-Induced Neurotoxicity using a human-relevant in vitro brain model](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/graph-based-modeling-detection-and-tracking-sarin-surrogate-induced-neurotoxicity-using-human-relevant-vitro-brain-model) | 23-LW-011 | Jose Cadena Pico | Lab-Wide | Continuing | | [Harnessing Organic Phosphorus Scavengers to Mitigate Nutrient Scarcity](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/harnessing-organic-phosphorus-scavengers-mitigate-nutrient-scarcity) | 23-LW-068 | Wei Li | Lab-Wide | Continuing | | [High-Resolution Bioprinted Hierarchical Lung Tissue Model for Studying Respiratory Threats](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/high-resolution-bioprinted-hierarchical-lung-tissue-model-studying-respiratory-threats) | 22-ERD-044 | Maxim Shusteff | Exploratory Research | Continuing | | [Host-Directed, Bioelectronic Immunomodulation for Protection Against Emerging Pathogens](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/host-directed-bioelectronic-immunomodulation-protection-against-emerging-pathogens) | 23-ERD-013 | Allison Yorita | Exploratory Research | Continuing | | [Investigating Fluorescent Amino Acids with Entangled Photon Pair Absorption](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/investigating-fluorescent-amino-acids-entangled-photon-pair-absorption) | 23-FS-022 | Audrey Eshun | Feasibility Study | Continuing | | [Invisible Organ: The Next Level of Human Health and Resilience](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/invisible-organ-next-level-human-health-and-resilience) | 22-SI-002 | Nicholas Be | Strategic Initiative | Continuing | | [Linking Protein Phase Separation to Amyotrophic Lateral Sclerosis Pathology with Physical Simulations](/archives/ldrd-annual-2023/project-highlights/bioscience-and-bioengineering/linking-protein-phase-separation-amyotrophic-lateral-sclerosis-pathology-physical-simulations) | 23-FS-056 | Joel Berry | Feasibility Study | Continuing | #### Pagination - [ Page 1](?page=0 "Current page") - [ Page 2](?page=1 "Go to page 2") - [ Next page Next › ](?page=1 "Go to next page") - [ Last page Last » ](?page=1 "Go to last page")