Catching Villains: Finding Single Cells Responsible for Cancer Drug Resistance and Metastasis

Erika Fong | 18-LW-046

Executive Summary

We will develop a platform to enable single-cell delivery and analysis using Lawrence Livermore National Laboratory's Accelerator Mass Spectrometer. Using this new capability and a mouse model, we will probe the response of individual cancer cells to drugs to identify any drug-resistant subpopulations of cells and the mechanisms for their resistance and spread.