Quantitative Viral Assessments for Improved Biomonitoring

Gareth Trubl | 21-LW-060

Executive Summary

We will develop and validate an innovative biomonitoring capability to detect and characterize all virus types in one sample to aid in developing novel countermeasures to biological and antibiotic-resistant pathogens. This capability is essential to protecting the nation from viral biological threats.

Publications, Presentations, and Patents

Chou, L., Grefenstette, N., Borges, S., Caro, T., Catalano, E., Harman, C.E., McKaig, J., Raj, C.G., Trubl, G., Young, A. "The Astrobiology Primer v3.0, Chapter 8: Searching for Life Beyond Earth." In review at Astrobiology. LLNL-JRNL-825389.

Colón-Santos, S., Vázquez-Salazar, A., Vincent , L., Adams , A.M., Muñoz-Velasco, I., Jácome, R., Hernández-Morales, R., Campillo-Balderas, J.A., Trubl, G. "The Astrobiology Primer v3.0, Chapter 2: What is Life?" In review at Astrobiology. LLNL-JRNL-825392.

Sommers P., Chatterjee A., Varsani A., Trubl G. "Integrating viral metagenomics into an ecological framework." Annual Review of Virology, 8. 2021. LLNL-JRNL-818035.

Szeinbaum, N., Bozdag, O., Garcia, A., Chen, K., Schaible, G.A., Trubl, G. "The Astrobiology Primer v3.0, Chapter 5: Major Biological Transitions in the History of Life on Earth." In review at Astrobiology. LLNL-JRNL-825388.

Trubl, G. “Unraveling the hidden potential of active microbial and viral communities in soil ecosystems.” In Phages for Health and Energy: Bridging National Lab and Academic Research Capabilities Agenda symposium. 2021. LLNL-PRES-826516.

Trubl, G. “Characterizing viruses for ecology, biotechnology, and health benefits.” In Georgetown Frontiers in Biotechnology. 2021. LLNL-PRES-82601.

Trubl, G. “Unraveling The Hidden Potential of Viruses in Soil Ecosystems Using Stable Isotope Probing Metagenomics.” In San Francisco State University Virology BIOL420. 2021. LLNL-PRES-821962.

Trubl, G. “Using SIP-metagenomics to characterize soil viruses.” In JGI virus group meeting. 2021. LLNL-PRES-820751.

Trubl, G. “Quantitative Viral Assessments for Improved Biomonitoring.” In Emerson lab meeting at UC-Davis. 2021. LLNL-PRES-820392.

Trubl, G. “Viruses in soil.” In 2nd grade class at Francophone charter school of Oakland, CA. 2021. LLNL-PRES-819810.