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An Investigational Platform of the Human Brain for Understanding Complex Neural Function

Nicholas Fischer

Executive Summary

We will develop a first-of-its-kind, validated, functional model of the central nervous system that recreates the human brain's microenvironment and architecture. Our work will address fundamental questions about complex neuronal interactions as they pertain to chemical exposures and associated countermeasures, as well as disease and its mitigation.

Publications and Presentations

Belle, A. M., et al. 2018. "Evaluation of In Vitro Neuronal Platforms as Surrogates for In Vivo Whole Brain Systems." Nature Scientific Reports 8 (10820). doi: 10.1038/s41598/s41598-018-28950-5. LLNL-JRNL-746078.