Lawrence Livermore National Laboratory

Bioscience and Bioengineering


LDRD Annual Report FY2019

Project Title Tracking Code Author Project Type Project Status
Characterizing Host–Pathogen Immunity Gut–Brain Interactions 16-ERD-007 Gabriela Loots Exploratory Research Final
A Computational Approach to Improve Prediction of Off-Target Drug Binding Using Membrane Bilayer Effects 18-ERD-035 Helgi Ingolfsson Exploratory Research Progress
A Deep Bayesian Active Learning Framework for Temporal Multimodal Data 19-ERD-009 Priyadip Ray Exploratory Research Progress
A Handheld Medical Diagnostic Device for Harsh Environments 18-ERD-045 Matthew Coleman Exploratory Research Final
A Machine Learning System to Guide Clinical Procedures in Real-Time 18-LW-078 Robert Blake Laboratory-Wide Competitions Final
An Investigational Platform of the Human Brain for Understanding Complex Neural Function 17-SI-002 Nicholas Fischer Strategic Initiatives Final
Antibacterial Minerals: A Geochemical Approach to Combating Antibiotic Resistance 19-LW-029 Keith Morrison Laboratory-Wide Competitions Progress
Bioprinting Breast Cancer In Situ to Study Cell Communication in Disease Progression 18-ERD-062 Claire Robertson Exploratory Research Progress
Brain Connectomics: Opportunities for High-Performance Computing 18-FS-009 Alan Kaplan Feasibility Study Final
Catching Villains: Finding Single Cells Responsible for Cancer Drug Resistance and Metastasis 18-LW-046 Erika Fong Laboratory-Wide Competitions Final
Computational Design of Broadly Neutralizing Vaccines for Highly Mutable Pathogens 17-ERD-043 Felice Lightstone Exploratory Research Final
Detection of Upwind Pathogens Using Aircraft and Ground Stations 18-ERD-044 Crystal Jaing Exploratory Research Final
Elucidating Algal–Bacterial Community Interactions by Tracking Volatile Biomarkers 19-FS-035 Matthias Frank Feasibility Study Progress
Engineered and Instrumented Three-Dimensional Tumor-Immune Model System 19-SI-003 Elizabeth Wheeler Strategic Initiatives Progress
Engineering a Therapeutic Microbe for Infection-Site Delivery of Encapsulated Antimicrobial Peptides 17-ERD-013 Mimi Yung Exploratory Research Final
Imaging Macromolecular Structural Dynamics with Low-Dose, Time-Resolved Transmission Electron Microscopy 19-FS-038 Joseph Mckeown Feasibility Study Final
Innate Persistence of Human Immune Memory T Cells 18-LW-037 Bruce Buchholz Laboratory-Wide Competitions Final
Investigating the Role of Innate Immunity in Viral Encephalitis Caused by Rift Valley Fever Virus 17-LW-038 Dina Weilhammer Laboratory-Wide Competitions Final
Longitudinal Monitoring of Ribonucleic Acid Content of a Live Cell with a Nanotube Pore Interface 18-ERD-011 Aleksandr Noy Exploratory Research Progress
Metamaterials for Mechanically Directing Cell Phenotype 19-FS-064 Karen Dubbin Feasibility Study Progress
Microbial Characterization of Combat-Patient Wounds to Improve Healing 17-ERD-031 Nicholas Be Exploratory Research Progress
Molecular Mechanisms of Bacterial Pathogenesis: Waging the Arms Race with Superbugs 19-LW-048 Brent Segelke Laboratory-Wide Competitions Progress
Optical Interconnect for High-Density Neural Signals 18-ERD-042 Razi-Ul Haque Exploratory Research Progress
Preparing Circulatory Modeling Code for Exascale Computing 19-FS-023 Erik Draeger Feasibility Study Final
Protein Factory on a Chip for Rapid Therapeutics 18-LW-055 Nicholas Watkins Laboratory-Wide Competitions Final
Rapid Detection of Candidates for Vaccines Against Biothreat Agents 18-LW-039 Magdalena Franco Laboratory-Wide Competitions Progress
Stable Isotope Probing and Viromics: Quantifying Virus-Host and Carbon Cycling Dynamics in Soil with Isotope-Targeted Metagenomics 18-ERD-041 Steven Blazewicz Exploratory Research Progress
Synthetic Biology and Computational Modeling for Prediction of Viral Virulence 17-ERD-019 Monica Borucki Exploratory Research Final
The Mechanochemical Genesis of Prebiotics 18-LW-036 Elissaios Stavrou Laboratory-Wide Competitions Final
Three-Dimensional Bio-Printed Microenvironments for Studying Cancer Metastasis 17-ERD-054 Monica Moya Exploratory Research Final
Three-Dimensional Bioprinted Aneurysm for Intervention Modeling Validation 19-LW-006 William Hynes Laboratory-Wide Competitions Progress
Toward Artificial Neurons: Biomimetic Signal Propagation in Synthetic Nanochannel Systems 18-LW-057 Steven Buchsbaum Laboratory-Wide Competitions Final
Using Microscale Models to Enhance Predictions of Damage to Soft Tissues 19-FS-070 Phillip Paul Feasibility Study Progress